You're looking for information on a specific patch for Fallout 4. Here's what I could gather:
Script Extender: Users on this version must use a specific version of the Fallout 4 Script Extender (F4SE) compatible with build 1.10.163 to ensure mod stability. Fallout 4 Update 1.10.163
Universal Compatibility: A vast majority of the most popular mods on Nexus Mods were designed for this version. While some have been updated for newer versions, many niche or "abandoned" gems only function correctly on 1.10.163. You're looking for information on a specific patch
Conclusion: Fallout 4 Update 1.10.163 represents a significant step forward in refining the gameplay experience. While not perfect, the patch demonstrates Bethesda's ongoing commitment to supporting and improving Fallout 4 long after its initial release. Players are encouraged to report any ongoing issues to help Bethesda prioritize future patches and updates. Mods using F4SE (Fallout 4 Script Extender) require
content, its "solid feature" today is actually its status as definitive stable version for modding Fallout Wiki
What the patch actually did (summary of concrete changes)